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- Select reagents and procedures that minimize the volume and toxicity of all  wastes. If feasible, design experiments in such a way that radioactive wastes are generated separately from chemically or biologically hazardous wastes   
 
- Avoid ordering radioactive materials in quantities that exceed your intended usage
 
- Non-radioactive wastes must never be mixed with radioactive wastes.  Failure to do this significantly increases the volume of wastes 
 
- Non-radioactive tracers and methods are available for many common assays, and procedures used in biomedical
 
- Substitute with Short-lived Radionuclides where feasible
 
- Reduce the activity and volumes of materials used in the experiment to decrease the amount of wastes generated
 
- Replace hazardous chemical solvents with formulations not regulated as hazardous or mixed wastes
 
- Limit the number of users of radioactive materials
 
- Limit the number of areas where radioactive materials are used 
 
NIH Policy Manual 3032   
NIH policy on environmental management  and waste minimization        
NIH Environmental Management System (NEMS) 
 
A management tool to help improve environmental performance and provide information on the NIH Goes Greener Campaign